SUPFAM Release 3.0 uses homologous families in Pfam (Version 23.0) and SCOP (Release 1.69) which are examples of sequence -alignment and structure classification databases respectively.

Check out here: SUPFAM
New Features of SUPFAM web-site
* New design!
* Use of ALignHUSH profile-profile alignment program to relate families.
* Graphical representation of superfamilies have been added.
by Krishnadev O
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